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January 2022

Clinical Update: 

NCCN Updates Guidelines 

for Treatment of Kidney Cancer!

Creator: SCIEPRO | Credit: Getty Images/Science Photo Libra

The National Comprehensive Cancer Network (NCCN) Guidelines for Kidney Cancer focus on the screening, diagnosis, staging, treatment, and management of renal cell carcinoma (RCC). All systemic kidney cancer therapy regimens were categorized to provide guidance on treatment selection by considering the efficacy, safety, evidence, and other factors that play a role in treatment selection. These factors include comorbidities, nature of the disease, access to agents and hereditary genetic risk. 


These updated guidelines include criteria for further genetic risk evaluation using a hereditary cancer panel for hereditary RCC syndromes: 

·       Close family history of known pathogenic variations or cancer, 

·       Diagnosed before the age of 46, 

·       Bilateral or multifocal tumors OR 

·       Tumors with certain histological characteristics.


The panels are recommended to contain 

VHL, MET, FLCN, TSC1, TSC2, FH, BAP1, SDHA, SDHB, SDHC and SDHD.


Genetics Institute of America’s GIAnomics™ Hereditary Cancer Panel includes all the recommended predisposition genes for RCC. GIA is committed to exceeding the standards put forth by prestigious organizations, like NCCN, and ensuring that the panels we offer support your medical needs and your patient’s health and safety.

   
   

Enroll your Practice in GH-101!


Genetics Institute of America is actively recruiting practices to join our study, GH-101! The objective of this study is to take an integrative approach to the fields of pharmacogenomics, cancer genomics, mRNA microarrays and nutrigenomics by identifying DNA and RNA variants in persons with chronic disease. We are looking for Physicians and Physician Groups that currently treat patients with a chronic disease including: cancer, cardiac conditions, diabetes, kidney disease, PTSD. Getting your practice involved is easy and not only gets patients the individualized health information they need but allows your practice to be on the cutting edge of genetic research. Click "Enroll Now" for more information about this study and enrolling your practice.


   

Have you Seen This?: 


High Prevalence of Germline Variations in Renal Cell Carcinoma Patients

   

According to the CDC, Renal Cell Carcinoma (RCC) affects over 65,000 patients per year making it among the top 10 most frequently diagnosed cancers in the United States.

It's All in the Genes:


Germline Variations in Prostate Cancer and Treatment Implications

   

Despite advancements in treatment and diagnosis, prostate cancer (shorthanded as PrCa in the literature) is the fifth leading cause of death for men worldwide and was the most diagnosed cancer in men living in North America.

Changing Corporate Culture:


Gifting Hope to Foster Families

Genetics Institute of America believes that it is our responsibility to care for the community we are a part of, and that corporate culture can do more to play a greater role in community solutions.


   
   
   

Thank you for the trust and confidence you have placed in our team here at the Genetics Institute of America. This monthly newsletter is our primary method of communicating to you important information about our testing and assays, general information about the Genetics Institute, as well as information impacting patient care and safety. If you would like to have another person in your practice receive these updates, please forward this to them so that they can subscribe.


   

Ana Perez-Miranda, PhD, MDxT (AAB), MB (ASCP)

Laboratory Manager and Molecular Diagnostics Supervisor

Genetics Institute of America
   

GIA Lab News is an educational service of Genetics Institute of America.


Genetics Institute of America is a national laboratory dedicated to heightening the awareness of early intervention and genetic screening to promote the longevity and quality of life outcomes. Our determination and research allow us to provide next generation DNA sequencing to deliver customized testing for identified genetic related cancers and other diseases.

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